What is a possible adverse effect of corticosteroids?

Corticosteroids are known to increase blood sugar levels, leading to a condition called hyperglycemia. This effect occurs because corticosteroids can stimulate gluconeogenesis in the liver and decrease glucose utilization by the tissues, which can result in elevated blood glucose levels. This is particularly important to monitor in patients who have diabetes or are at risk for developing diabetes, as it can complicate their management.

In contrast, weight loss, increased energy levels, and decreased appetite are not commonly associated effects of corticosteroids. In fact, corticosteroids often lead to weight gain due to increased appetite and fat deposition, rather than decreased appetite. Understanding the metabolic effects of corticosteroids is vital for managing their side effects effectively and ensuring patient safety.