What is a classic symptom of appendicitis?

Right lower quadrant pain is indeed a classic symptom of appendicitis. The appendix is located in the right lower quadrant of the abdomen, and when it becomes inflamed, the pain often begins around the navel (periumbilical area) and then migrates to the right lower quadrant. This movement of pain is characteristic of appendicitis and can be accompanied by tenderness upon palpation in that area.

In addition to the pain, patients may also experience additional symptoms such as fever, nausea, and changes in bowel habits. The specificity of the right lower quadrant pain in appendicitis is crucial for diagnosis, as it helps differentiate it from other abdominal conditions that may present with different pain patterns.

The other choices present symptoms that are either too vague or relate to different conditions. For example, left upper quadrant pain might suggest splenic or gastric issues, general abdominal discomfort is too nonspecific to pinpoint appendicitis, and severe chest pain is more indicative of cardiac or pulmonary conditions rather than gastrointestinal ones.